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We investigated structural differences in the fatty acid profiles of lipids extracted from ex vivo contact lenses by using gas chromatography mass spectrometry (GCMS). Two lens materials (balafilcon A or lotrafilcon A) were worn on a daily or continuous wear schedule for 30 and 7 days.

Evidence of Lipid Degradation During Overnight Contact Lens Wear: Gas Chromatography Mass Spectrometry as the Diagnostic Tool