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The herpes simplex virus type 1 (HSV-1) U(S)1 gene encodes host-range and ocular virulence determinants. Mutations in U(S)1 affecting virulence are known in strain OD4, but the genomic variation across several strains is not known. The goal was to determine the degree of sequence variation in the gene from several ocular HSV isolates.

Sequence Variation in the Herpes Simplex Virus US1 Ocular Virulence Determinant

Sequence Variation in the Herpes Simplex Virus U_S1 Ocular Virulence Determinant