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Myopia is a common vision problem affecting almost one third of the world's population. It can occur as an isolated genetic condition or be associated with other anomalies and/or syndromes. Seventeen myopia loci have been identified on various chromosomes; however, no specific gene mutations have yet been identified.

investigative ophthalmology and visual science

Refinement of the X-linked Nonsyndromic High-Grade Myopia Locus<i>MYP1</i>on Xq28 and Exclusion of 13 Known Positional Candidate Genes by Direct Sequencing

Refinement of the X-linked Nonsyndromic High-Grade Myopia LocusMYP1on Xq28 and Exclusion of 13 Known Positional Candidate Genes by Direct Sequencing