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Blue-light photooxidative damage has been implicated in the etiology of age-related macular degeneration (AMD). The macular pigment xanthophylls lutein (L) and zeaxanthin (Z) and n-3 fatty acids may reduce this damage and lower the risk of AMD. This study investigated the effects of the lifelong absence of xanthophylls followed by L or Z supplementation, combined with the effects of n-3 fatty acid deficiency, on acute blue-light photochemical damage.

investigative ophthalmology and visual science

Nutritional Manipulation of Primate Retinas, V: Effects of Lutein, Zeaxanthin, and<i>n</i>–3 Fatty Acids on Retinal Sensitivity to Blue-Light–Induced Damage

Nutritional Manipulation of Primate Retinas, V: Effects of Lutein, Zeaxanthin, andn–3 Fatty Acids on Retinal Sensitivity to Blue-Light–Induced Damage