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This paper examines the relationship between international human rights regimes and the pursuit of United Sates national interests in the 21st century. Archival research or literature survey, content analysis, and the realist theory of international human rights were adopted for the inquiry. The core objectives of the paper were to assess US human rights posture; find out if US international defence of human rights and interventions is without bias; and to determine if there is a positive relationship between US pursuit of national interest and US human rights policy. The results of analysis show that US has both internal and external poor human rights posture; and that lack of neutrality on US international campaign. The results further reveal that there is no generally accepted principles of human rights and its institutions; and although the international human rights regime lacks jurisdiction over the US, it has consistently being used to advance US national interests in the international system. Among others, the paper recommends an international conference of sovereignties to harmonise the principles and institutions of international human rights, and for the regime to have jurisdiction over all sovereignties.

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International Human Rights Regime as Instrument for Advancing National Interests: The US and Others Since the 20&amp;lt;sup&amp;gt;th&amp;lt;/sup&amp;gt; Century