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A new species of Centromedon Sars, 1891 is described based on abundant material collected in baited traps at 2500 m on the Mid-Atlantic Ridge. The species can be distinguished from the most closely allied species, Centromedon typhlops (Sars, 1879), Centromedon mediator (Barnard, 1962) comb. nov. and Centromedon laevis (Bonnier, 1896) comb. nov., by the form of the gnathopods, and characters of the mouthparts. A key to the eight species in the genus is provided. The differences between the closely allied genera Uristes Dana, 1849 and Centromedon are discussed.

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Centromedon zoe (Crustacea: Amphipoda: Lysianassoidea: Uristidae), a new deep-water scavenger species from the North Atlantic, with a key to the genus Centromedon