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bicarbonate improves outcome in prolonged prehospital cardiac arrest. Am J Emerg Med 2006;24:156–161. 6. Kudenchuk PJ, Brown SP, Daya M, Rea T, Nichol G, Morrison LJ, et al.; Resuscitation Outcomes Consortium Investigators. Amiodarone, lidocaine, or placebo in out-of-hospital cardiac arrest. N Engl J Med 2016;374:1711–1722. 7. Nichol G, Leroux B, Wang H, Callaway CW, Sopko G, Weisfeldt M, et al.; ROC Investigators. Trial of continuous or interrupted chest compressions during CPR. N Engl J Med 2015;373:2203– 2214. 8. Grieco DL, Brochard L, Drouet A, Telias I, Delisle S, Bronchti G, et al.; CAVIAR Group. Intrathoracic airway closure impacts CO2 signal and delivered ventilation during cardiopulmonary resuscitation. Am J Respir Crit Care Med 2019;199:728–737. 9. Jabre P, Penaloza A, Pinero D, Duchateau FX, Borron SW, Javaudin F, et al. Effect of bag-mask ventilation vs endotracheal intubation during cardiopulmonary resuscitation on neurological outcome after out-ofhospital cardiorespiratory arrest: a randomized clinical trial. JAMA 2018;319:779–787. 10. Morgan RW, Sutton RM, Karlsson M, Lautz AJ, Mavroudis CD, Landis WP, et al. Pulmonary vasodilator therapy in shock-associated cardiac arrest. Am J Respir Crit Care Med 2018;197:905–912.

When the Fetus Is Exposed to Smoke, the Developing Lung Is Burned