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Platelets are believed to contribute to acute respiratory distress syndrome (ARDS) pathogenesis through inflammatory coagulation pathways. We recently reported that leucine-rich repeat-containing 16A (LRRC16A) modulates baseline platelet counts to mediate ARDS risk.

american journal of respiratory and critical care medicine

A Missense Genetic Variant in <i>LRRC16A</i>/<i>CARMIL1</i> Improves Acute Respiratory Distress Syndrome Survival by Attenuating Platelet Count Decline

A Missense Genetic Variant in LRRC16A/CARMIL1 Improves Acute Respiratory Distress Syndrome Survival by Attenuating Platelet Count Decline