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Infection with Pneumocystis, an opportunistic fungal pathogen, can result in fulminant pneumonia in the clinical setting of patients with immunosuppression. In murine models, Pneumocystis has previously been shown to induce a CD4 + T cell-dependent eosinophilic response in the lung capable of providing protection.

A Novel CD4+ T Cell–Dependent Murine Model of Pneumocystis-driven Asthma-like Pathology

A Novel CD4⁺ T Cell–Dependent Murine Model of Pneumocystis-driven Asthma-like Pathology