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P142 The purpose of this study was to determine the frequency,  timing of occurrence, and predictors of selected complications and  medical disorders following cerebral infarction (CI) in a  population-based study. The Rochester Epidemiology Project medical  records linkage system was used to identify all first cerebral  infarctions (CI) among Rochester, Minnesota residents during  1985–1989. The comprehensive medical records were reviewed; past  history and demographic data, post-CI complications, and cause of death  were recorded. CI subtype, severity, and site were determined. The  frequency, timing and predictors of complications after CI were  determined using the Kaplan-Meier product limit method and Cox  proportional hazards regression analysis. A total of 444 first cerebral  infarctions (181 men, 263 women; mean age 75.3 years) were identified  among residents of Rochester, Minnesota, during 1985–1989. During a  follow-up of up to 10 years, some of the complications and other  medical disorders included chest infection in 194 (44%), a fall  requiring medical attention in 122 (27%), myocardial infarction in 84  (19%), seizure in 38 (9%), and PE in 14 (3%). The risk of chest  infection after CI was 11% at 30 days, 22% at 1 year, and 40% at 5  years. The risk of seizure was 2% at 30 days, 4% at one year, and 9%  at 5 years. Regression analysis revealed that stroke severity, prior  history of COPD, older age, swallowing dysfunction requiring a PEG, and  stroke recurrence were significant independent predictors of chest  infection after first CI. Use of aspirin after CI was inversely related  to occurrence of chest infection. Complications are common after  cerebral infarction. Some of the complications are more likely to occur  early after the CI. Increased awareness of these issues may lead to  enhanced complication prevention techniques, and surveillance for the  complications. The study provides unique population-based data  regarding predictors of the important causes of morbidity and mortality  following cerebral infarction, and may be compared to other  non-population based data.

Medical Complications Following Cerebral Infarction: Frequency, Timing, and Predictors in a Population-Based Study.