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We thank Nahmod et al1 for their interest in our studies and for their intriguing experiments with dendritic cells that corroborate and complement our findings. One limitation of the bone marrow transfer strategy is that this approach does not elucidate which specific mononuclear cell populations are mediating blood pressure elevation and/or tissue damage. Therefore, experiments like those conducted by Nahmod et al1 will be crucial in defining the precise roles of angiotensin II type 1 (AT1) receptors on individual immune cell lineages in regulating inflammation. Reconciling the results of the diverse studies exploring the functions of AT1 receptors on immune cells is indeed challenging, …

Response to Angiotensin II Type 1a–Deficient Bone Marrow–Derived Dendritic Cells Produce Higher Levels of Monocyte Chemoattractant Protein 1