Open AccessAbnormal Epicardial Coronary Resistance in Patients With Diffuse Atherosclerosis but “Normal” Coronary Angiography
Author(s) -
Bernard De Bruyne,
Ferry MRJ Hersbach,
Nico H.J. Pijls,
Jozef Bartúnek,
Jan-Willem Bech,
Guy R. Heyndrickx,
K. Lance Gould,
William Wijns
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/hc4501.099316
Subject(s) - medicine , cardiology , coronary arteries , stenosis , artery , fractional flow reserve , angiography , coronary artery disease , vascular resistance , blood pressure , coronary angiography , myocardial infarction
Coronary arteries without focal stenosis at angiography are generally considered non-flow-limiting. However, atherosclerosis is a diffuse process that often remains invisible at angiography. Accordingly, we hypothesized that in patients with coronary artery disease, nonstenotic coronary arteries induce a decrease in pressure along their length due to diffuse coronary atherosclerosis.
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