Open AccessPathological Analysis of Local Delivery of Paclitaxel Via a Polymer-Coated Stent
Author(s) -
Andrew Farb,
Phillip F. Heller,
Sweta Shroff,
Linda Cheng,
Frank D. Kolodgie,
Andrew J. Carter,
Douglas Scott,
Jeffrey P. Froehlich,
Renu Virmani
Publication year - 2001
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/hc3001.092037
Subject(s) - paclitaxel , medicine , restenosis , stent , drug delivery , neointima , urology , surgery , chemotherapy , materials science , nanotechnology
Paclitaxel can inhibit vascular smooth muscle proliferation in vitro, and early studies suggest that paclitaxel may be useful in preventing restenosis. Early and late intimal growth and local vascular pathological changes associated with paclitaxel delivered via stents have not been fully explored.
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