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ADAMs (A Disintegrin And Metalloproteinase) are ectoproteases that have recently been reported to be expressed in cardiac tissue. Although they are known to regulate cell-cell and cell-matrix interactions, their pathophysiological role in various cardiac diseases is unclear. The purpose of the present study was to determine whether structural remodeling of the atria during atrial fibrillation (AF) is associated with altered ADAM expression.

Altered Expression of ADAMs ( A D isintegrin A nd M etalloproteinase) in Fibrillating Human Atria

**Altered Expression of ADAMs ( A D isintegrin A nd M etalloproteinase) in Fibrillating Human Atria**