Open AccessIdentification and Classification of Acute Cardiac Rejection by Intragraft Transcriptional Profiling
Author(s) -
Cécile Holweg,
Luciano Potena,
Helen Luikart,
Tianwei Yu,
Gerald J. Berry,
John P. Cooke,
Hannah A. Valantine,
Edward S. Mocarski
Publication year - 2011
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/circulationaha.109.913921
Subject(s) - medicine , lung transplantation , heart transplantation , endomyocardial biopsy , transplantation , gene expression profiling , pathology , lung , gene expression , biopsy , gene , biology , genetics
Treatment of acute rejection (AR) in heart transplantation relies on histopathological grading of endomyocardial biopsies according to International Society for Heart and Lung Transplantation guidelines. Intragraft gene expression profiling may be a way to complement histological evaluation.
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