Open AccessReprogramming the Cardiac Field
Author(s) -
Erik Willems,
Mark Mercola
Publication year - 2014
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/circresaha.113.302946
Subject(s) - reprogramming , field (mathematics) , computer science , medicine , biology , genetics , mathematics , cell , pure mathematics
Two recent reports show that it is possible to reprogram somatic cells to a stem cell state using only a chemical cocktail or by inducing genes in tissues of engineered mice. These studies herald a time when cellular plasticity can be manipulated directly in the body to regenerate damaged tissues and organs. How do we go from these milestones to therapeutic heart regeneration?
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