Open AccessMacrophage-Derived Matrix Vesicles
Author(s) -
Sophie E. P. New,
Claudia Goettsch,
Masanori Aikawa,
Júlio Flávio Meirelles Marchini,
Manabu Shibasaki,
Katsumi Yabusaki,
Peter Libby,
Catherine M. Shanahan,
Kevin Croce,
Elena Aïkawa
Publication year - 2013
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/circresaha.113.301036
Subject(s) - phosphatidylserine , microvesicle , annexin , calcification , macrophage , microbiology and biotechnology , microvesicles , chemistry , vesicle , microcalcification , pathology , biology , cancer research , medicine , in vitro , biochemistry , membrane , phospholipid , gene , microrna , breast cancer , mammography , cancer
We previously showed that early calcification of atherosclerotic plaques associates with macrophage accumulation. Chronic renal disease and mineral imbalance accelerate calcification and the subsequent release of matrix vesicles (MVs), precursors of microcalcification.
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