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We thank you for the opportunity to respond to the commentary from Banerjee et al, regarding our publication “Essential Role for Thymosin β4 in Regulating Vascular Smooth Muscle Cell Development and Vessel Wall Stability.”See Research Commentary, p e25 The discrepancies between our findings and those of Banerjee et al were outlined in our original article1 and plausible explanations provided, which were acceptable to the reviewers of our article. We reiterate below our rationale and data, which support a role for thymosin β4 (Tβ4) in mural cell development (in addition to those presented in our original publication). We did not, as stated in the Banerjee commentary, report impaired mural cell migration.

Thymosin β4 in Vascular Development Response to Research Commentary