Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase
Author(s) -
Katrin Schröder,
Min Zhang,
Sebastian Benkhoff,
Anja Mieth,
Rainer U. Pliquett,
Judith Kosowski,
Christoph Kruse,
Peter Luedike,
Uwe Michaelis,
Norbert Weißmann,
Stefanie Dimmeler,
Ajay M. Shah,
Ralf P. Brandes
Publication year - 2012
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/circresaha.112.267054
Subject(s) - nox4 , nadph oxidase , angiotensin ii , chemistry , nox1 , nitric oxide synthase , oxidative stress , nitric oxide , nicotinamide adenine dinucleotide phosphate , biology , endocrinology , medicine , microbiology and biotechnology , biochemistry , oxidase test , receptor , enzyme
The function of Nox4, a source of vascular H(2)O(2), is unknown. Other Nox proteins were identified as mediators of endothelial dysfunction.
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