Open AccessMitotically Inactivated Embryonic Stem Cells Can Be Used as an In Vivo Feeder Layer to Nurse Damaged Myocardium after Acute Myocardial Infarction
Author(s) -
Richard K. Burt,
You-hong Chen,
Larissa Verda,
Carolina Lucena,
Shankararao Navale,
Jesse Johnson,
Xiaoqiang Han,
Jon W. Lomasney,
Jessa M. Baker,
Ka-Leung Ngai,
Aya Kino,
James Carr,
Jan Kajstura,
Piero Anversa
Publication year - 2012
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/circresaha.111.262584
Subject(s) - cardiac function curve , stem cell , ex vivo , biology , in vivo , embryonic stem cell , myocardial infarction , paracrine signalling , medicine , microbiology and biotechnology , heart failure , gene , receptor , biochemistry
Various types of viable stem cells have been reported to result in modest improvement in cardiac function after acute myocardial infarction. The mechanisms for improvement from different stem cell populations remain unknown.
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