Open AccessPlasmacytoid Dendritic Cells Protect Against Atherosclerosis by Tuning T-Cell Proliferation and Activity
Author(s) -
Isabelle Daissormont,
Anette Christ,
Lieve Temmerman,
Stefan Sampedro Millares,
Tom Seijkens,
Marco Manca,
Mat Rousch,
Marjorie Poggi,
Louis Boon,
Chris van der Loos,
Mat J.A.P. Daemen,
Esther Lutgens,
Bente Halvorsen,
Pål Aukrust,
Edith M. Janssen,
Erik A.L. Biessen
Publication year - 2011
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/circresaha.111.256529
Subject(s) - biology , immunology , dendritic cell , interferon , cell growth , plasmacytoid dendritic cell , foam cell , cell , t cell , cross presentation , lymphatic system , microbiology and biotechnology , lesion , cancer research , macrophage , antigen presentation , medicine , immune system , pathology , in vitro , genetics , biochemistry
Unlike conventional dendritic cells, plasmacytoid DCs (PDC) are poor in antigen presentation and critical for type I interferon response. Though proposed to be present in human atherosclerotic lesions, their role in atherosclerosis remains elusive.
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