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The molecular correlate of the calcium release-activated calcium current (I(CRAC)), the channel protein Orai1, is upregulated in proliferative vascular smooth muscle cells (VSMC). However, the role of Orai1 in vascular disease remains largely unknown.

Orai1-Mediated I CRAC Is Essential for Neointima Formation After Vascular Injury

Orai1-Mediated I _CRAC Is Essential for Neointima Formation After Vascular Injury