Open AccessChronic Electrical Neuronal Stimulation Increases Cardiac Parasympathetic Tone by Eliciting Neurotrophic Effects
Author(s) -
Obaida R. Rana,
Erol Saygili,
Christopher Gemein,
Matthias Daniel Zink,
A. J. Buhr,
Esra Saygılı,
Karl Mischke,
Kay Nolte,
Joachim Weis,
Christian Weber,
Nikolaus Marx,
Patrick Schauerte
Publication year - 2011
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/circresaha.110.234518
Subject(s) - stimulation , tone (literature) , parasympathetic nervous system , medicine , neurotrophic factors , neuroscience , electric stimulation , endocrinology , neurotrophin , psychology , autonomic nervous system , heart rate , blood pressure , receptor , literature , art
Recently, we provided a technique of chronic high-frequency electric stimulation (HFES) of the right inferior ganglionated plexus for ventricular rate control during atrial fibrillation in dogs and humans. In these experiments, we observed a decrease of the intrinsic ventricular rate during the first 4 to 5 months when HFES was intermittently shut off.
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