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Effects of Vascular and Nonvascular Adverse Events and of Extended-Release Niacin With Laropiprant on Health and Healthcare Costs
Author(s) -
Seamus Kent,
Richard Haynes,
Jemma C. Hopewell,
Sarah Parish,
Alastair Gray,
Martin Landray,
Rory Collins,
Jane Armitage,
Borislava Mihaylova
Publication year - 2016
Publication title -
circulation cardiovascular quality and outcomes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.692
H-Index - 87
eISSN - 1941-7713
pISSN - 1941-7705
DOI - 10.1161/circoutcomes.115.002592
Subject(s) - niacin , medicine , adverse effect , quality of life (healthcare) , randomized controlled trial , placebo , alternative medicine , pathology , nursing
Extended-release niacin with laropiprant did not significantly reduce the risk of major vascular events and increased the risk of serious adverse events in Heart Protection Study 2-Treatment of HDL to Reduce the Incidence of Vascular Events (HPS2-THRIVE), but its net effects on health and healthcare costs are unknown.

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