Open AccessAnalysis for Genetic Modifiers of Disease Severity in Patients With Long-QT Syndrome Type 2
Author(s) -
I. Kolder,
Michael W.T. Tanck,
Pieter G. Postema,
Julien Barc,
Moritz F. Sinner,
Sven Zumhagen,
Anja Husemann,
Birgit Stallmeyer,
Tamara T. Koopmann,
Nynke Hofman,
Arne Pfeufer,
Peter Lichtner,
Thomas Meitinger,
Britt Maria Beckmann,
Robert J. Myerburg,
Nanette H. Bishopric,
Dan M. Roden,
Stefan Kääb,
Arthur A.M. Wilde,
JeanJacques Schott,
Eric SchulzeBahr,
Connie R. Bezzina
Publication year - 2015
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-3268
pISSN - 1942-325X
DOI - 10.1161/circgenetics.114.000785
Subject(s) - qt interval , single nucleotide polymorphism , odds ratio , long qt syndrome , confidence interval , population , medicine , genetics , allele , biology , cardiology , bioinformatics , genotype , gene , environmental health
Considerable interest exists in the identification of genetic modifiers of disease severity in the long-QT syndrome (LQTS) as their identification may contribute to refinement of risk stratification.
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