Large-Scale Candidate Gene Analysis in Whites and African Americans Identifies IL6R Polymorphism in Relation to Atrial Fibrillation
Author(s) -
Renate B. Schnabel,
Kathleen F. Kerr,
Steven A. Lubitz,
Ermeg L. Alkylbekova,
Gregory M. Marcus,
Moritz F. Sinner,
Jared W. Magnani,
Philip A. Wolf,
Rajat Deo,
Donald M. LloydJones,
Kathryn L. Lunetta,
Reena Mehra,
Daniel Levy,
Ervin R. Fox,
Dan E. Arking,
Thomas H. Mosley,
Martina MüllerNurasyid,
Taylor Young,
H.Erich Wichmann,
Sudha Seshadri,
Deborah Farlow,
Jerome I. Rotter,
Elsayed Z. Soliman,
Nicole L. Glazer,
James G. Wilson,
Monique M.B. Breteler,
a Sotoodehnia,
Christopher NewtonCheh,
Stefan Kääb,
Patrick T. Ellinor,
Álvaro Alonso,
Emelia J. Benjamin,
Susan R. Heckbert
Publication year - 2011
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-325X
pISSN - 1942-3268
DOI - 10.1161/circgenetics.110.959197
Subject(s) - medicine , single nucleotide polymorphism , atrial fibrillation , candidate gene , hazard ratio , genome wide association study , stroke (engine) , confidence interval , genetics , bioinformatics , genotype , gene , biology , mechanical engineering , engineering
The genetic background of atrial fibrillation (AF) in whites and African Americans is largely unknown. Genes in cardiovascular pathways have not been systematically investigated.
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