Open AccessGenetic and Clinical Correlates of Early-Outgrowth Colony-Forming Units
Author(s) -
Stanley Y. Shaw,
Susan Cheng,
L. Adrienne Cupples,
Martin G. Larson,
Elizabeth L. McCabe,
Julius S. Ngwa,
Ying A. Wang,
Roderick P. Martin,
Rachael Klein,
Basma Hashmi,
Olujimi A. Ajijola,
Evan Lau,
Christopher J. O’Donnell,
Ramachandran S. Vasan,
Kenneth S. Cohen,
Thomas J. Wang
Publication year - 2011
Publication title -
circulation cardiovascular genetics
Language(s) - English
Resource type - Journals
eISSN - 1942-325X
pISSN - 1942-3268
DOI - 10.1161/circgenetics.110.958470
Subject(s) - locus (genetics) , framingham heart study , allele , myocardial infarction , framingham risk score , medicine , biology , disease , genetics , immunology , endocrinology , gene
Several bone marrow-derived cell populations may have angiogenic activity, including cells termed endothelial progenitor cells. Decreased numbers of circulating angiogenic cell populations have been associated with increased cardiovascular risk. However, few data exist from large, unselected samples, and the genetic determinants of these traits are unclear.
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