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We were pleased to see the results of the validation work done by Barra et al1 in examining the performance of the REPLACE (Death After Replacement Evaluation) DARE score2 in their patient population. The DARE score results in their implantable cardioverter-defibrillator (ICD) replacement group of 228 patients yielded findings that were consistent, and, for some metrics, nearly identical, to those found in the REPLACE population of 1744 patients, despite a longer follow-up period (33 months versus 6 months in REPLACE).We also appreciated the additional efforts by Barra et al1 to compare the DARE score performance to the predictive model proposed by Bilchick et al,3 which was developed on a larger population of Medicare patients (n=17 991) receiving de novo ICD implantation for primary prevention. Although the final risk model of Bilchick et al3 was based on 7 predictor variables in a related but somewhat different patient population with a longer average follow-up (4.4 years), the concordance with 5 of the 6 predictor variables used …

circulation. arrhythmia and electrophysiology

Response to Letter Regarding “REPLACE DARE (Death After Replacement Evaluation) Score: Determinants of All-Cause Mortality After Implantable Device Replacement Or Upgrade From the REPLACE Registry”