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Elevated Circulating Lipocalin-2 Levels Independently Predict Incident Cardiovascular Events in Men in a Population-Based Cohort
Author(s) -
Guangyu Wu,
Huating Li,
Qichen Fang,
Shan Jiang,
Lei Zhang,
Jing Zhang,
Xuhong Hou,
Junxi Lu,
Yuqian Bao,
Aimin Xu,
Weiping Jia
Publication year - 2014
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.114.303718
Subject(s) - medicine , cohort , population , lipocalin , environmental health
Adipose tissue inflammation and perturbation of adipokine secretion may contribute to the pathogenesis of cardiovascular diseases (CVD). Lipocalin-2 (LCN2), mainly released from adipocytes, has been shown to be positively associated with CVD in cross-sectional studies. We aimed to evaluate the association of LCN2 with CVD involving a population-based cohort recruited from the Shanghai Diabetes Study.

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