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Macrophage apoptosis plays important roles in atherosclerosis. Bcl-2 is a key cell survival molecule, but its role in macrophage apoptosis in atherosclerosis is not known. The goal herein was to determine the effect of macrophage-targeted deletion of Bcl-2 on macrophage apoptosis in atherosclerotic lesions of Apoe(-/-) mice.

Brief Report: Increased Apoptosis in Advanced Atherosclerotic Lesions of Apoe −/− Mice Lacking Macrophage Bcl-2

Brief Report: Increased Apoptosis in Advanced Atherosclerotic Lesions of Apoe ^−/− Mice Lacking Macrophage Bcl-2