USF1 Gene Variants, Cardiovascular Risk, and Mortality in European Americans | Zendy

Alexander P. Reiner | Zendy; Christopher S. Carlson | Zendy; Nancy S. Jenny | Zendy; Jon Peter Durda | Zendy; David S. Siscovick | Zendy; Deborah A. Nickerson | Zendy; Russell P. Tracy | Zendy

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USF1 Gene Variants, Cardiovascular Risk, and Mortality in European Americans

Author(s) -

Alexander P. Reiner,

Christopher S. Carlson,

Nancy S. Jenny,

Jon Peter Durda,

David S. Siscovick,

Deborah A. Nickerson,

Russell P. Tracy

Publication year - 2007

Publication title -

arteriosclerosis thrombosis and vascular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.007

H-Index - 270

eISSN - 1524-4636

pISSN - 1079-5642

DOI - 10.1161/atvbaha.107.154559

Subject(s) - dyslipidemia , medicine , odds ratio , linkage disequilibrium , genotype , allele , haplotype , disease , genetics , biology , gene

A common haplotype of the upstream transcription factor 1 gene (USF1) has been associated with decreased susceptibility to familial combined hyperlipidemia (FCHL) and, paradoxically, with increased risk of cardiovascular disease (CVD) and all-cause mortality.

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