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Novel Mechanism and Role of Angiotensin II–Induced Vascular Endothelial Injury in Hypertensive Diastolic Heart Failure
Author(s) -
Eiichiro Yamamoto,
Keiichiro Kataoka,
Haruo Shintaku,
Takuro Yamashita,
Yoshiko Tokutomi,
YiFei Dong,
Shinji Matsuba,
Hidenori Ichijo,
Hisao Ogawa,
Shokei KimMitsuyama
Publication year - 2007
Publication title -
arteriosclerosis thrombosis and vascular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.007
H-Index - 270
eISSN - 1524-4636
pISSN - 1079-5642
DOI - 10.1161/atvbaha.107.153692
Subject(s) - enos , medicine , endocrinology , valsartan , endothelial dysfunction , angiotensin ii , amlodipine , heart failure , angiotensin ii receptor type 1 , endothelium , biology , nitric oxide , blood pressure , nitric oxide synthase
The mechanism and role of angiotensin II-induced vascular endothelial injury is unclear. We examined the molecular mechanism of angiotensin (AII)-induced vascular endothelial injury and its significance for hypertensive diastolic heart failure.

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