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Subarachnoid hemolysate (SAH) has been associated with oxidative brain injury, cell death, and apoptosis. We hypothesized that over-expression of CuZn-superoxide dismutase (CuZn-SOD) would protect against injury after SAH, whereas reduction of its expression would exacerbate injury.

Cell Death After Exposure to Subarachnoid Hemolysate Correlates Inversely With Expression of CuZn–Superoxide Dismutase