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To the Editor:The formulation of evidence-based stroke care practice guidelines is guided by the results of randomized trials. We sought to determine what proportion of all trial reports are published in Stroke , and what proportion might be missed by electronic search methods.One of us (B.T.) performed a page-by-page search of every issue of Stroke (1970–2001), applying standard criteria1 to identify all reports of relevant randomized trials and controlled clinical trials appearing in articles, editorials, letters, conference abstracts, or any other text. Reports of trials of interventions for the treatment, rehabilitation, and secondary prevention of stroke are included in the Cochrane Stroke Group Trials Register. Reports of trials outside the scope of the Group are forwarded for inclusion in the Cochrane Central Register of Controlled Trials in the Cochrane Library. We developed a detailed search strategy for MEDLINE, which includes controlled vocabulary and …

Contribution of Stroke to the Cochrane Stroke Group Trials Register