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ATP-sensitive K+ (K(ATP)) channels have been implicated in the mechanism of neuronal ischemic preconditioning. To evaluate the role of neuronal/beta-cell-type K(ATP) channels, SUR1 null (Sur1KO) mice lacking (K(IR)6.x/SUR1)(4) K(ATP) channels were subjected to a preconditioning protocol with the use of double carotid occlusion.

Ischemic Preconditioning in the Hippocampus of a Knockout Mouse Lacking SUR1-Based K ATP Channels

Ischemic Preconditioning in the Hippocampus of a Knockout Mouse Lacking SUR1-Based K _ATP Channels