Responses of Dog's Pad Vessels to Epinephrine Following Sympathectomy or Denervation | Zendy

Theodore Cooper | Zendy; Vallee L. Willman | Zendy; Alrick B. Hertzman | Zendy

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Responses of Dog's Pad Vessels to Epinephrine Following Sympathectomy or Denervation

Author(s) -

Theodore Cooper,

Vallee L. Willman,

Alrick B. Hertzman

Publication year - 1959

Publication title -

circulation research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.899

H-Index - 336

eISSN - 1524-4571

pISSN - 0009-7330

DOI - 10.1161/01.res.7.4.574

Subject(s) - epinephrine , sympathectomy , denervation , hindlimb , medicine , adrenergic , anesthesia , endocrinology , receptor

Augmented reactivity of the skin vessels of the hind limbs of dogs to doses of l-epinephrine in the physiologic range could not be detected following conventional sympathectomy. Larger doses of epinephrine resulted in exaggerated reactions. Augmented reactivity of these vessels to physiologic doses of epinephrine was detectable if total cholinergic as well as adrenergic denervation of the limb was accomplished.

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