Open AccessRenal Hemodynamics, Electrolyte Excretion and Water Metabolism in Pregnant Sheep Before and After the Induction of Toxemia of Pregnancy
Author(s) -
N.S. Assali,
L. W. Holm,
Donald L. Hutchinson
Publication year - 1958
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/01.res.6.4.468
Subject(s) - hemodynamics , pregnancy , endocrinology , medicine , excretion , kidney , renal ischemia , renal physiology , ischemia , metabolism , blood pressure , physiology , biology , reperfusion injury , genetics
Renal hemodynamics, electrolyte excretion and plasma level of glucorticoids were studied in pregnant sheep before and after the experimental induction of toxemia. Marked renal ischemia occurred in the animals which developed toxemia. This abnormality occurred concomitantly with an increase in plasma corticoids. Despite the renal ischemia, arterial pressure remained the same. There are some similarities between the toxemia of the sheep and that of human pregnancy.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom