Open AccessInfluence of Digitoxin on Labile and Inorganic Phosphates, Lactate, Glycogen, Potassium and Sodium in Dog Ventricle
Author(s) -
JOHN REBAR,
Blanche T. Rebar,
Akira Omachi
Publication year - 1957
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/01.res.5.5.504
Subject(s) - digitoxin , glycogen , potassium , chemistry , sodium , sodium lactate , ventricle , medicine , endocrinology , phosphate , digitalis , sugar phosphates , metabolism , biochemistry , biology , digoxin , heart failure , organic chemistry
This communication deals with the effects produced by digitoxin on the metabolism of the dog's ventricles as indicated by changes in labile and inorganic phosphates, lactate, glycogen, potassium and sodium content of the myocardium immediately frozen after excision. The results suggest increased turnover of high energy phosphate and glycogen by nontoxic doses.
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