Open AccessAction of Human Plasma on the Isolated Frog Heart
Author(s) -
Stephen Hajdu,
Edward J. Leonard,
R. P. Akers
Publication year - 1957
Publication title -
circulation research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.899
H-Index - 336
eISSN - 1524-4571
pISSN - 0009-7330
DOI - 10.1161/01.res.5.3.319
Subject(s) - medicine , human plasma , essential hypertension , human heart , cardiology , plasma levels , endocrinology , plasma , plasma concentration , chemistry , blood pressure , physics , quantum mechanics , chromatography
Plasma samples from certain patients affect the staircase phenomenon of the frog heart. Comparison of 3 groups of subjects, normal controls, patients without essential hypertension, and patients with severe essential hypertension shows that plasmas from the last group generally abolish the staircase, whereas plasmas of the other 2 groups exhibit little or no such activity.
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