In Vivo Incorporation of Acetate-1-C 14 into Cholesterol and Fatty Acids Following Testosterone Propionate Administration

The administration of testosterone propionate for three weeks resulted in an increased incorporation of sodium acetate-1-C14 into cholesterol and fatty acids. This increased conversion was evident in both the plain-mash and the atherogenic-diet cockerels. Thus, the hypocholesterolemic effect of testosterone propionate is not the result of a decreased synthesis of cholesterol and/or fatty acids. In addition, a trend towards lowering of the plasma and tissue cholesterol levels of the atherogenic-diet animals is indicated.