Open AccessImpact of Aortic Stiffness on Survival in End-Stage Renal Disease
Author(s) -
Jacques Blacher,
Alain P. Guérin,
Bruno Pannier,
Sylvain J. Marchais,
Michel E. Safar,
Gérard M. London
Publication year - 1999
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.99.18.2434
Subject(s) - medicine , pulse wave velocity , arterial stiffness , cardiology , end stage renal disease , pulse pressure , cohort , population , hemodialysis , blood pressure , confounding , kidney disease , surgery , environmental health
Damage to large arteries is a major factor in the high cardiovascular morbidity and mortality of patients with end-stage renal disease (ESRD). Increased arterial stiffness and intima-media thickness, together with increased pulse pressure, are the principal arterial alterations. Whether increased aortic pulse-wave velocity (PWV), a classic marker of increased arterial stiffness, may predict all-cause and/or cardiovascular mortality has never been investigated.
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