Open AccessAssociation of the α-Fibrinogen Thr312Ala Polymorphism With Poststroke Mortality in Subjects With Atrial Fibrillation
Author(s) -
Angela M. Carter,
Andrew J. Catto,
Peter J. Grant
Publication year - 1999
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.99.18.2423
Subject(s) - medicine , atrial fibrillation , fibrinogen , cardiology , association (psychology) , polymorphism (computer science) , genotype , genetics , epistemology , biology , gene , philosophy
The alpha-fibrinogen Thr312Ala polymorphism occurs in close proximity to several sites important for factor XIIIa-dependent cross-linking, which raises the possibility that it affects fibrin clot stability.
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