Open AccessHydrogen Peroxide, Potassium Currents, and Membrane Potential in Human Endothelial Cells
Author(s) -
Rostislav Bychkov,
Knud Pieper,
Christian Ried,
Marianna Milosheva,
Eugen Bychkov,
Friedrich C. Luft,
Hermann Haller
Publication year - 1999
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.99.13.1719
Subject(s) - depolarization , hyperpolarization (physics) , membrane potential , biophysics , reactive oxygen species , hydrogen peroxide , catalase , redox , reversal potential , patch clamp , intracellular , potassium channel , superoxide dismutase , electrophysiology , chemistry , biochemistry , oxidative stress , medicine , biology , inorganic chemistry , stereochemistry , nuclear magnetic resonance spectroscopy
Hydrogen peroxide (H2O2) and reactive oxygen species are implicated in inflammation, ischemia-reperfusion injury, and atherosclerosis. The role of ion channels has not been previously explored.
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