Open AccessModulated Dispersion Explains Changes in Arrhythmia Vulnerability During Premature Stimulation of the Heart
Author(s) -
Kenneth R. Laurita,
Steven Girouard,
Fadi G. Akar,
David Rosenbaum
Publication year - 1998
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.98.24.2774
Subject(s) - repolarization , cardiology , medicine , optical mapping , stimulation , ventricular fibrillation , stimulus (psychology) , electrophysiology , qt interval , fibrillation , heart rate , atrial fibrillation , blood pressure , psychology , psychotherapist
Previously, we have shown that a premature stimulus can significantly modulate spatial gradients of ventricular repolarization (ie, modulated dispersion), which result from heterogeneous electrophysiological properties between cells. The role modulated dispersion may play in determining electrical instability in the heart is unknown.
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