Open AccessGene Polymorphisms for Plasminogen Activator Inhibitor-1/Tissue Plasminogen Activator and Development of Allograft Coronary Artery Disease
Author(s) -
Raymond L. Benza,
Hernan E. Grenett,
Robert C. Bourge,
James K. Kirklin,
David C. Naftel,
Pablo Castro,
David C. McGiffin,
James F. George,
François M. Booyse
Publication year - 1998
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.98.21.2248
Subject(s) - genotype , plasminogen activator inhibitor 1 , plasminogen activator , medicine , hindiii , t plasminogen activator , tissue plasminogen activator , coronary artery disease , fibrinolysis , immunology , biology , gene , genetics , restriction enzyme
Impaired fibrinolytic activity has been linked to the presence and severity of allograft vasculopathy (Tx CAD). This impairment may be associated with the presence of certain fibrinolytic protein gene polymorphisms.
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