Open AccessChanges in passive mechanical stiffness of myocardial tissue with aneurysm formation.
Author(s) -
K B Gupta,
Mark B. Ratcliffe,
Michael Fallert,
L H Edmunds,
D.K. Bogen
Publication year - 1994
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.89.5.2315
Subject(s) - myocardial infarction , medicine , ligation , cardiology , stiffness , infarction , hydroxyproline , biomedical engineering , materials science , composite material
Myocardium undergoes complex cellular and histochemical alterations after acute myocardial infarction. These structural changes directly affect the mechanical stiffness of infarcted and remote myocardia. Previous investigations of infarct stiffness have been limited to uniaxial testing, which does not provide a unique description of the tissue's three-dimensional material properties. This study describes the first serial measurements of biaxial mechanical properties of sheep myocardium after anteroapical infarction.
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