Platelet activation during coronary angioplasty in humans.
Author(s) -
Christine M. Gasperetti,
Steven L. Gonias,
Lawrence W. Gimple,
Eric R. Powers
Publication year - 1993
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.88.6.2728
Subject(s) - medicine , angioplasty , cardiology , platelet , coronary sinus , epinephrine , thrombus , platelet activation , balloon , iopamidol , anesthesia , serotonin , contrast medium , radiology , receptor
Previous studies have indicated that balloon angioplasty is associated with local platelet activation. In addition, different contrast media have different effects on thrombus formation during angioplasty in humans. We hypothesized that coronary angioplasty in humans is associated with activation of platelets to specific platelet agonists and that this activation may be differently modified by different angiographic contrast agents.
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