Open AccessRole of oscillatory potential and pacemaker shifts in digitalis intoxication of the sinoatrial node.
Author(s) -
Mario D. González,
Mario Vassalle
Publication year - 1993
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.87.5.1705
Subject(s) - diastolic depolarization , sinoatrial node , ouabain , medicine , tetrodotoxin , digitalis , digoxin , calcium , endocrinology , acetylcholine , atrioventricular node , cardiology , tachycardia , chemistry , heart rate , sodium , blood pressure , heart failure , organic chemistry
Digitalis intoxication causes tachycardia, pacemaker shifts, and conduction disturbances in the sinoatrial (SA) node, but the mechanisms underlying these changes have not been clarified. We studied the role played by oscillatory potentials, electrical inhomogeneity, and calcium overload in cardiac steroid intoxication of the SA node.
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