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Adrenergic effects on reentrant ventricular rhythms in subacute myocardial infarction.
Author(s) -
Ghazwan Butrous,
William B. Gough,
Mark Restivo,
Hua Yang,
Nabil ElSherif
Publication year - 1992
Publication title -
circulation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.795
H-Index - 607
eISSN - 1524-4539
pISSN - 0009-7322
DOI - 10.1161/01.cir.86.1.247
Subject(s) - refractory period , medicine , reentry , cardiology , myocardial infarction , infarction , ventricular fibrillation , stimulation , effective refractory period , anesthesia
Reentry has been shown to be a mechanism of ventricular arrhythmias elicited by programmed premature stimulation in the subacute ischemic period of dogs subjected to myocardial infarction. The spatial distribution of refractoriness in these hearts has been shown to play an important part in the formation of functional arcs of conduction block during programmed ventricular stimulation. Because the adrenergic nervous system influences cardiac arrhythmias and myocardial infarction can directly affect sympathetic innervation in the heart, we investigated the role of the sympathetic nervous system on reentry in the canine heart 4 days after infarction.

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