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Summary and Discussion A striking association between physical *The difference in mortality between "leastactive" and "most active" white collar workers is statistically significant at the 0.01 level; for the cor- responding groups in the blue collar category thedifference is significant at the 0.05 level. Circulation, Volume XXXIV, December 1966 inactivity and early mortality from the initial myocardial infarction in men less than 65 years of age has been shown. The data were derived from the first clinically manifest in- farctions occurring in a population of some 55,000 male adults enrolled in the Health In-surance Plan of Greater New York during anobservation period of 18 months (301 cases).Inquiry about customary physical activitieson and off the job has permitted delineationof a group of "least active" men who are muchmore likely to experience a clinically severe episode and die within 4 weeks of its onset than men who are relatively moreactive. More

Physical Inactivity as a Lethal Factor in Myocardial Infarction among Men